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Introduction Cardiovascular disease (CVD) is the main cause of morbidity and mortality in patients with type 2 diabetes (T2DM), with a relevant impact on the economic costs for health care systems and on the quality of life for many patients ( Among the novel therapies, great interest has been aroused by sodiumglucose cotransporter-2 inhibitors (SGLT2-i) and glucagon-like peptide-1 receptor agonist (GLP1-RA), that have changed the management of diabetic patients

This process can leave your stool hard, dry, and difficult to pass

Many patients benefit from ongoing behavioral counseling or participation in structured weight management programs

This increase in GLP-1 causes the stomach to empty more slowly, extending the feeling of fullness, and also works in the brain to reduce appetite