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2012 Int J Mol Sci

JAMA Netw Open 2024;7:e2421305.ArticlePubMedPMC 11

After six months, weight loss often plateaus as your body adapts to the medication and the benefits of calorie restriction reach an equilibrium

A study published in August 2025 found that lean muscle mass loss via a mouse model was less than previous studies had reported, and also found that a good portion of the And research presented at the European Congress on Obesity (ECO 2025) reported that adults taking GLP-1 drugs were able to retain muscle while losing weight by strength training and eating enough protein