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when cellular energy is sufficient, mTORC1 is activated to drive cell proliferation (90), whereas low ATP levels activate AMPK, which phosphorylates TSC2, stabilizing the TSC complex and inhibiting mTORC1 (91)

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In human studies, curcumin supply resulted in a decrease in muscle damage and inflammatory biomarkers, with an approximate dosage of 1501500 mg/day administered pre-, post-, and during exercise, potentially enhancing athletic performance and muscle repair by mitigating exercise-induced muscle injury and modulating the inflammatory reaction (565, 566)

Different effects and mechanisms of selenium compounds in improving pathology in Alzheimers disease