By addressing these aspects of glucose metabolism, GLP-1 agonists have become crucial tools in managing type 2 diabetes and, more recently, obesity
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Key death receptor-ligand pairs include Fas (APO-1/CD95)-FasL (CD95L), TNFR1 (DR1)-TNF, TRAILR1 (DR4)-TRAIL (APO-2L), TRAILR2 (DR5)-TRAIL (APO-2L), and DR3 (APO-3/TRAMP)-TL1A (Newton et al., 2024)
