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The clinical translation of ferroptosis-targeted strategies is as well significantly hindered by the restriction of disease models, which involves the discrepancy between preclinical models and clinical settings

The clinical manifestation of selenosis includes symptoms such as gastrointestinal disturbances, hair loss, neurological dysfunction, and nail abnormalities [101]

The combination AZT plus indinavir induced an increase in ROS production, disruption in membrane mitochondrial potential, reduction in intracellular GSH levels, augment permeability of endothelial layer, leading cell death [49]

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