The natural hormone does three things
doi: 10.1007/s11102-014-0582-9 124 Romn GonzlezAPadilla ZambranoHSLpez MontoyaVGutirrezJBuiles-BarreraCA
Dietary and lifestyle interventions include: Consuming smaller, more frequent meals rather than large portions that increase gastric distension Avoiding late evening meals and maintaining at least a 3-hour interval between dinner and bedtime Limiting foods that relax the lower esophageal sphincter (chocolate, peppermint, high-fat foods, caffeine, alcohol) Reducing acidic and spicy foods that may irritate the esophageal mucosa Elevating the head of the bed by 6-8 inches using blocks or a wedge pillow Maintaining upright posture for at least 2-3 hours after eating Avoiding tight-fitting clothing around the abdomen Smoking cessation (if applicable) Continuing weight loss efforts, as weight reduction is an evidence-based therapy for GERD [16] [21] Pharmacologic management may be necessary for persistent symptoms
Its 3-letter sequence, Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Asn-His (31 residues as tabulated with N-terminal modification), features a single methionine that analysts should note as a potential oxidation site during method development, alongside multiple basic residues (Arg, Lys, His) that dominate its charge state envelope in positive-mode ESI-MS
