molecular hydrogen nrf2 glutathione Activation, interaction and intimation of pathway and their mutational studies causing Nrf2 associated cancer NRF2-mediated pathway of glutathione synthesis.

In BMAL1/ mice, the GH receptor (GHR) signaling was decreased, including reduced phosphorylation of GHR, JAK2, and STAT1/3/5

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On the other hand, increased levels of taurine were reported in retinoblastoma, glioblastoma, and medulloblastoma in vivo [53, 54]

Acknowledgements This research was supported by National Key R&D Program of China (2021YFF0702600), the National Natural Science Foundation of China (82222056 and 82111530099), Guangdong Special Young Talent Plan of Scientific and Technological Innovation (2019TQ05Y510), the Natural Science Foundation of Guangdong (2022A1515012316), the Guangdong International Joint Research Program (2020A0505100027), and National Key Clinical Discipline