There are also serious side effects that can happen, but are rare, which can include: pancreatitis, medullary thyroid cancer, acute kidney injury and worsening diabetes-related retinopathy
In a 2020 review, the researchers corroborated that silymarin's capacity to reduce oxidative stress on the liver could indeed improve biomarkers associated with conditions such as alcoholic fatty liver disease, nonalcoholic fatty liver disease, alcoholic cirrhosis, and drug-induced liver injury.29 Although the studies covered in the review used 420mg silymarin doses, others have found that amounts as low as 200mg could also impart the desired effects on liver health.30 If that weren't all, a 2018 study concluded that silymarin may actually increase glutathione levels in the liver.31 Selenium (55mcg) Selenium is an essential mineral with antioxidant properties, and one that may increase levels of an enzyme called glutathione peroxidase (GPx).32 GPx is important because it uses reduced glutathione to neutralize hydrogen peroxide,33 one of the major ROS
Most activity occurs in areas with high fat concentration like the abdomen and thighs
Drug Interactions That Affect Monitoring Frequency Several co-administered medications alter copper metabolism and require tighter monitoring when combined with GHK-Cu
