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At the 12mg dose, retatrutide reduced HbA1c by 2.2 percentage points over 36 weeks while simultaneously producing 16.9% body weight reduction a dual glycemic and metabolic benefit not observed at comparable levels with single or dual agonists

A lack of vitamin B12 doesnt directly lead to weight gain, however, so getting a B12 injection alone wont cause you to lose weight no matter how many times your doctor calls the injection a skinny shot

In such cases, self-injection kits offer a practical way to keep the cost of B12 injections low

Sean Hashmi, MD Medical Reviewer Sean Hashmi, MD, is an experienced nephrologist and obesity medicine specialist based in Southern California