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During Phase I metabolism, various enzymes catalyze oxidation, reduction, and hydrolysis reactions, leading to the formulation of metabolites with altered chemical structures compared to the parent compounds

At the same time, I would say that iCare is best understood as a fast-launch private label partner rather than a deep formulation collaborator

The reduced form is inherently unstable and has virtually zero oral bioavailability, which until now has limited the benefits of supplementation.

Compelling findings from germ-free (GF) animal studies have demonstrated that the absence of microbiota leads to substantial neurodevelopmental abnormalities and altered behavior (Sudo et al., 2004