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doi:10.1093/oxfordjournals.molbev.a004166

Competing interests The authors take full responsibility for the content and conclusions stated in this manuscript

ELIXA trial included patients with recent cardiovascular event (patients with acute coronary syndrome 180 days before randomization), and although there was no benefit in MACE reduction in lixisenatide treated patients compared to placebo, results revealed cardiovascular safety of lixisenatide in this specific high risk population (45)