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The ABR wave-I amplitude, which represents cochlear nerve activity, can provide an objective measure of cochlear synaptopathy when cochlear thresholds and associated hair cell function remain normal 16 , while the wave V, generated in the lateral lemniscus and inferior colliculus 44 , is commonly used to evaluate central auditory gain

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This review aims to synthesize the recent progress of omics technologies in the realm of OA, aspiring to furnish theoretical foundations and research orientations for more profound studies of OA in the future