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These findings suggest a potential beneficial effect of semaglutide on glycemic status, but whether semaglutide treatment delays or prevents progression to type 2 diabetes requires confirmation

Similarly, the microbial conversion of bile acids into their secondary forms follows a diurnal pattern and provides a mechanism through which gut bacteria modulate FXR- and TGR5-dependent signaling in the liver (52, 58)

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However, in recent years, dedifferentiation, senescence and other forms of cell death, such as autophagy, pyroptosis and ferroptosis, have been found to be involved in the loss of cells