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Importantly, the FDA-approved product VYLEESI treats for premenopausal women with acquired, generalized hypoactive sexual desire disorder (HSDD) that causes marked distress or interpersonal difficulty and is not due to another medical or psychiatric condition, relationship problems, or the effects of a medication or drug substance

Patients with T2DM initiating GLP-1 RAs or metformin as first-line monotherapy were included (87,229 matched patients per cohort).The researchers found that compared with metformin, GLP-1 RA use was associated with a significantly lower risk for overall dementia, Alzheimer disease, and nonvascular dementias (adjusted hazard ratios, 0.90, 0.88, and 0.75, respectively)

00:07:55 Steve Small: Yeah, well, this is feeling clear as mud, but thank you so much for sharing your knowledge there