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Retatrutide is an investigational triple agonist targeting GLP-1, GIP, and glucagon receptors simultaneously, but it remains unlicensed in the UK and is only available within regulated clinical trials

This is the first step in being able to use someones genetic make-up to help us improve that decision-making process. The study is the first in-depth investigation of GLP-1 resistance, but the researchers have yet to pin down the mechanism

In addition, a representative from the American Association of Clinical Endocrinology (AACE) (GEU) was appointed to the taskforce

Secondary endpoints were changes in the Hepatic Encephalopathy Scoring Algorithm (HESA), venous ammonia, and tolerability