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Abstract Clinical and pre-clinical evidence demonstrates that adolescent -9-tetrahydrocannabinol (THC) exposure, the primary psychoactive component of cannabis, increases the risk of developing neuropsychiatric symptoms in later life

After the plasma membrane carrier-mediated GSH release from the cell, GSH becomes accessible to the active site of - glutamyl transpeptidase, which catalyzes the breakdown of the GSH - glutamyl bond forming two fractions: The -glutamyl fraction and the cysteinyl-glycine by transferring the -glutamyl fraction to an amino acid acceptor, forming -glutamyl-amino acid