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The results revealed that the expression of MYH7 and ANP were significantly elevated in TAC group, compared to the Sham group, but their expression in the TAC + semaglutide group were markedly reduced, compare to the TAC group, by Western blot and IHC respectively
Overall, indirect comparisons suggest that SGLT2 inhibitors may offer greater preservation of eGFR than GLP-1 receptor agonists in a broader population of people with type 2 diabetes mellitus and CKD
Starting with a lower dose and gradually increasing it can help minimize these effects
Both Semaglutide and Tirzepatide work by mimicking incretin hormonessignals released after meals that help regulate appetite, improve digestion, and lower blood sugar
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