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It has been reported that prostaglandin levels are higher in the brains of AD patients than in control brains 69,70

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As atherosclerotic plaques develop and advance, coronary blood flow becomes increasingly restricted, particularly during periods of elevated myocardial oxygen demand such as physical exertion or emotional stress

A polymorphism in SRI that codes for sorcin, associated with the secretion of serpin E5 and CCL5 inflammatory cytokines, also triggers -cell dysfunction ( Figure 3 ) (89)