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The net effect: adipocytes become metabolically sluggish, oxidizing less fat, storing more energy, and resisting signals that would normally promote energy expenditure

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Dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist, which means it mimics the action of these incretin hormones to enhance insulin secretion, suppress glucagon release, and slow gastric emptying

Final thoughts Tesofensine represents a powerful weight loss compound with proven 10-12% average weight loss through triple monoamine reuptake inhibition targeting dopamine, norepinephrine, and serotonin