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Multiple clinical trials and controlled studies have demonstrated: Statistically significant improvements in skin firmness and elasticity with consistent use Reduction in fine lines and wrinkle depth over 3-6 months of application Improved skin density, moisture retention, and surface texture Reduction in photodamage and hyperpigmentation Tightening of loose skin documented in both topical and injectable applications Citation: Leyden JJ et al

Comparison of Predicted and Actual Consequences of Missense Mutations

So one daily dose provides steady metabolic support throughout the day, without the hassle of remembering multiple doses