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Potential Research Applications: Glucose metabolism and insulin signaling pathway studies Mitochondrial function and cellular energy regulation research Metabolic pathway modulation and energy homeostasis models Mitochondrial-derived peptide activity and cellular signaling investigations For laboratory research use only

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Inhibition of mitochondrial adaptations and improvements in cardiorespiratory fitness by 50 percent and diminished whole-body insulin sensitivity after aerobic exercise 6 Metformin inhibits mitochondrial adaptations to aerobic exercise training in older adults Konopka et al (2018)