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Neither group responded to naloxone when given prior to ALC administration, however, the low LH group responded nicely with an increase in LH (normal response) after the 16 weeks (with a three-fold higher max LH pulse and overall 8-fold increase in amount of LH secreted)

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The preservative (if used) may be ineffective to inhibit microbial growth and cause sterility problems Patient Implication: A patient may be dispensed a 10 mL bottle of semaglutide with a BUD of 30 days