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The supernatant of tumor cells treated with Ru(II)-OH, NP2, and NP4 was co-cultured with RAW264.7 macrophages, and the intracellular calcium levels in macrophages were evaluated (Fig

In addition to inhibiting NF-kB signaling, riboflavin can also inhibit critical components of the non-canonical inflammasomes, such as caspase-1 activity 47 , either via the AIM2 cytosolic innate immune receptor, which recognizes double-stranded DNA (dsDNA) released during cellular perturbation, or via the Nod-like receptor NLRC4, which recognizes bacterial ligands such as flagellin and the type three secretion system (T3SS) 47

This no-nonsense formula is enriched with the ultimate skin perfector to brighten and tighten, while Niacinamide minimizes pores and maximizes radiance

Abbreviations: ALD, alcoholic liver disease