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Individual response to GLP-1 medications varies meaningfully variants in GLP1R (the GLP-1 receptor itself), GIPR (which matters specifically for tirzepatide's dual-agonist mechanism), FTO (appetite regulation), MC4R (satiety signaling), and TCF7L2 (insulin response) are associated with different weight-loss curves and different tolerability profiles

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On top of that, they can carry real risks, including: 8 Infections at the injection site Long-term hormone problems, especially for teens who are still growing Headaches, fatigue, and nausea Other unknown long-term effects Peptides for muscle growth and recovery Teen bodies already produce high levels of growth hormones naturally

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