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Whilst its classical role involves stimulating insulin secretion in response to food intake, emerging research has revealed that GLP-1 exerts significant effects beyond glucose regulation

When you take a GLP-1 medication, you're mimicking this natural process at a higher, more consistent levelessentially amplifying your body's own satiety signals

This was long considered counterproductive because glucagon raises blood sugar

Clinical Evidence: Frequency and Severity in Trial Data Major GLP-1 trials (SUSTAIN, STEP, and RISE studies) reported headache incidence of 58% in treatment arms versus 46% in placebo groupsa modest but meaningful difference