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These findings underscore FSP1s independent role in tumor maintenance and its potential as a stand-alone therapeutic target

Because of this dual action, tirzepatide may: Reduce appetite Improve insulin sensitivity Slow digestion Enhance metabolic regulation This broader hormonal activity may explain why some patients experience strong weight loss results with tirzepatide

Furthermore, Figure 4D confirmed that H 2 O 2 increased the content of cellular ROS, while both targeting peptides obviously reduced the fluorescence intensity of the cellular ROS probe compared to that of GHK, especially RGD-GHK inhibited approximately 40% of ROS production