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The progression from hepatic steatosis to steatohepatitis and cirrhosis is closely related to OS, lipotoxicity, and local inflammation [62,63]

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The 10-year cumulative incidence of MACE was 23.7% (95% CI 20.027.6%) in the metabolic surgery group and 34.0% (95% CI 28.144.2%) in the GLP-1 RA group (adjusted HR 0.65 (95% CI 0.510.82)