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If DPP-4 inhibitors exert any effect to inhibit sodium transport in the proximal tubule, this action does not appear to be mediated by potentiation of GLP-1 and or by pathways linked to the GLP-1 receptor [98,99,100,101]

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We then hypothesized that different dietary habits may modify the effects of carnitine supplementation on TMAO productivity, and still found that TMAO productivity in low producers increased significantly regardless of their dietary patterns (Figure S2c-d)