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Its the part of the protocol the trials didnt measure

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The medication's effect on gastric emptying can exacerbate pre-existing gastroesophageal reflux disease (GERD), potentially causing retrosternal burning or pressure that mimics cardiac symptoms

Topical NSAIDs are preferred over oral NSAIDs, especially in patients with kidney disease, heart failure, or those taking ACE inhibitors, ARBs, or diuretics For patients with more significant symptoms, physical therapy evaluation can be valuable for assessing biomechanics, providing targeted strengthening exercises, and addressing any movement pattern abnormalities that may contribute to joint stress