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Cell Metabolism 13 , 376388 (2011)

To investigate whether GCG, VGF, SCG2, SCG3, and CHGA contribute to hyperglucagonemia in individuals with diabetes and diabetic mice, we examined gene expression data from cells in patients with type 2 diabetes (GSE84133) 42 and high-fat diet (HFD)-induced obese mice (GSE203151) 43

Whether this reflects individual variation, absorption issues with the oral formulation, or quality concerns with specific batches is difficult to determine from reviews alone

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