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At present, the most frequently used method is estimation of eGFR using the CKD-EPI creatinine equation, which is implemented in practically all hospital and health center laboratories.13,14 Cystatin C-based methods have the disadvantage of being expensive and not commonly implemented in laboratories, but are likely more reliable, especially in older populations or patients with illness other than CKD (heart failure, cancer, malnutrition, cirrhosis) and its measurement is advocated by some guidelines

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75 Regarding Metabolic Associated Steatotic Liver Disease (MASLD), both liraglutide and exenatide have shown significant reductions in liver fat as well as liver enzymes and indices of fibrosis, while semaglutide compared to placebo resulted in MASLD resolution in 59% and improvements in hepatic fibrosis, decreasing disease progression