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Intraocular pressure was assessed in normal rats, and values between 13 and 19 mmHg were considered normal, in accordance with previous rat data ( To assess the effect of retrobulbar administration itself, the values were assessed before retrobulbar application, after retrobulbar application of saline (0.1 ml/each eye), BPC 157 1 g/0.1 ml saline/each eye, or L-NAME 0.5 mg/0.1 ml saline/each eye, at 1, 2, 4, 6, 8, and 10 min thereafter

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It is a structural failure of one of the most complex and poorly vascularized tissues in the human body, and that lack of blood supply is precisely what makes disc injuries so stubbornly resistant to healing