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Furthermore, DNases I and PAD4 inhibitors, which are key players in inhibiting NETs, have exhibited anti-inflammatory effects in conditions such as NETs-related kidney injury and acute respiratory distress syndrome (140, 141)

Rats metabolize faster, heal faster, and have different tissue architecture than humans

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KDM4A-mediated histone demethylation of SLC7A11 inhibits cell ferroptosis in osteosarcoma