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According to FDA prescribing information, these include nausea (12-24%), diarrhea (7-23%), decreased appetite (10-19%), vomiting (2-11%), constipation (5-17%), and dyspepsia (5-9%), with rates varying by dose and indication

Topamax affects neuronal signalling and metabolism, whilst Wegovy primarily influences appetite regulation and glucose homeostasis through hormonal mechanisms

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