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Most users achieve optimal results with twice-daily application (morning and evening) using well-formulated products at appropriate concentrations, though those with very sensitive skin or using stronger formulations may benefit from once-daily evening application or every-other-day protocols building tolerance gradually before increasing to daily use following peptide cycling principles

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Ongoing costs are higher

Among those who used a GLP-1 or GLP-1/GIP medication for weight loss in the past year, 85.0% [79.390.7%] used a medication licensed for weight loss in Great Britain69.5% [62.067.0%] reported using Mounjaro, 20.0% [12.927.0%] Wegovy, and 3.3% [0.06.8%] Saxenda (note that participants could select multiple medications, so these values sum to more than the total