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Endometriosis is an oestrogen-dependent inflammatory condition that can affect body weight and metabolism, though individual experiences vary considerably

Procedures like gastric sleeve , gastric bypass , and revision surgery produce average excess weight loss of 60 to 80% and substantial improvements in bariatric surgery for sleep apnea , diabetes, hypertension, and joint pain

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Diabetes and obesity, both of which are associated with the secretion of pro-inflammatory adipokines and the reduced availability of nitric oxide, may lead to the occurrence of HFpEF in young individuals due to myocardial remodeling and fibrosis [7, 34]