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Other common gastrointestinal effects include: Vomiting (5-24% of patients) Diarrhea (8-30% of patients) Constipation (10-24% of patients) Abdominal pain or discomfort (5-20% of patients) These side effects are typically most pronounced when initiating therapy or increasing doses, and often diminish over time as the body adjusts to the medication

26.8%, 61.6%, and +2.5% (case 2)

Moreover, GSH degradation and subsequent cysteine recycling pathway is associated with ovarian cancer as seen in peripheral blood serum from patients

Godoy, G., Travassos, P., Antunes, M., Iwanaga, C., SNakanishi, A., Curi, R., & Bazotte, R