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It reacts with Cys under the catalysis of cystathionine--synthetase to produce cystathionine, which is cleaved by cystathionine--lyase to form homocysteine

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The severity of many poisonings from drugs, alcohol, heavy metals and environmental toxins are related to an acute depletion of cellular glutathione

it competitively binds to cellular receptors, blocking the body's natural active B6 and potentially inducing a functional deficiency that leads to peripheral neuropathy (nerve tingling and pain)