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The degree to which autophagy induction leads to observable enhancements in human metabolic health, especially among individuals with T2DM or metabolic syndrome, is still not fully understood [27]

A thorough understanding of how different metabolite fluxes intersect and influence each others impact on drug uptake and antibiotic resistance is needed in order to exploit the full potential of metabolic reprogramming and facilitate development of successful metabolism-based strategies to combat antibiotic resistance