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Nakao Y, Mori M, Sekiguchi Y, Morita I, Shindoh R, Mandai S, Fujiki T, Kikuchi H, Ando F, Susa K, Mori T, Waseda Y, Yoshida S, Fujii Y, Sohara E, Uchida S, Mori Y (2024) Recapitulation of Cellular Senescence, Inflammation, and Fibrosis in Human Kidney-Derived Tubuloids by Repeated Cisplatin Treatment: A Novel Pathophysiological Model for Sensing Nephrotoxicity and Drug Screening
These compounds address underlying pathology including collagen disorganization, persistent inflammation, and impaired blood supply
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