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doi: 10.1002/1099-1492(200010)13:6 3.0.CO;2-C

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Its essential to consult a medical professional if these symptoms persist or if unexpected reactions arise after treatment

Constitutive activity of MOR was suggested to be increased after chronic exposure to morphine on the basis of responses to proposed neutral versus inverse agonists in cultured cell lines and animals (Liu and Prather, 2001