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Free radicals play critical role in generating oxidative stress, which oxidizes dopamine to dopamine quinone and superoxide anion and decreases the NADPH and dopamine metabolized by MOA that produces the 3,4-dihydroxyphenylacetaldehyde, ammonia, and H 2 O 2 , which in turn interacts with Fe ++ to generates the OH free radicals that kill neurons in PD [61, 62]

This improved adhesion is crucial because it fosters the colonization of beneficial bacteria, which is necessary for maintaining gut homeostasis and supporting immune modulation which may be beneficial in alleviating conditions such as SLE (164)

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Cancer Res 64, 7197200