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Cancer epidemiology context LeRoith & Roberts (2003) and Pollak (2008) summarize the body of evidence linking elevated circulating IGF-1 to risk of certain cancers

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Furthermore, the patented active ingredient Mtabolaid, derived from a unique blend of lemon verbena and hibiscus extracts, has been clinically studied to demonstrate its effectiveness in weight management and fat mass reduction

These associations involve chronic endogenous elevation, but they establish the biological plausibility of concern for long-acting exogenous analogues [8]