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Overexpression of SLC7A10 in mature white adipocytes was observed to reduce ROS generation and enhanced suppression of SLC7A10 had the opposite impact, suggesting that SLC7A10 supports a beneficial increase in mitochondrial activity within white adipocytes [98]

Front Pharmacol 14:1146960 [DOI] [PMC free article] [PubMed] [Google Scholar] Gupta S et al (2021) SiRNA mediated GSK3 knockdown targets insulin signaling pathway and rescues Alzheimers disease pathology: evidence from in vitro and in vivo studies