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In the end, the best weight loss medication is the one that a patient finds helpful, easy to use, and effective over time, which can also reduce the risk of cardiovascular disease

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And, as critics have pointed out over the years, by elevating just one, two, or at most, three researchers, the Nobels distort the history of science by personalizing discoveries that are truly made by groups of individuals. That reality hangs heavy especially over a decision about GLP-1 and other gut-hormone based drugs, given how much additional science had to be done to convert the hormones to effective, and then even more effective, drugs

A pleiotropic missense variant in SLC39A8 is associated with Crohns disease and human gut microbiome composition