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Semaglutide works through a single receptor, GLP-1

Common drugs that have been implicated in the development of NS are Diclofenac, topical anesthetics (lidocaine), vaccines, corticosteroids, antihistamines, polidocanol, and pegylated interferon-alpha, glatiramer acetate, Bismuth salicylate, Interferon alpha, Oxytocin, Acetaminophen (Paracetamol), B complex vitamins, Bortezomib, Calcium hydroxide, Ceftriaxone, Epinephrine, and Ketorolac.[] The etiology is unclear

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A 10 mg vial covers ~4 weeks at maintenance dose (2.4 mg/week)