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The wide variety of vaping device types, vaping flavors, and varying nicotine concentrations have made the study of health effects difficult for researchers(12, 13)

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Treatment with PLS was demonstrated to reduce oxidative stress, lower inflammatory scores, and decrease cox-2 expression, suggesting its promising potential in treating UC [151]

This study provides evidence for a previously undiscovered mechanism that describes how 25(OH)VD deficiency/inadequacy is linked to lower GSH levels and that boosting GSH status beneficially upregulates the genes of VD metabolism and VDR , both of which are needed to increase the bioavailability and blood levels of 25(OH)VD and reduce inflammation levels