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This pathway not only promotes proliferation but also alters mitochondrial bioenergetics in ways that support survival under therapeutic stress [70, 71]

Vitamin C: Stimulates collagen synthesis and assists in antioxidant protection against UV-induced photodamage

Second, cagrilintide slows gastric emptying by inhibiting vagal efferent signalling to the stomach, reducing the rate at which the pyloric sphincter allows food into the small intestine

However, existing iron chelators exhibit side effects in clinical applications, including gastrointestinal discomfort, hepatotoxicity, and nephrotoxicity ( Based on TfR1-mediated iron uptake and ferroptosis mechanisms, researchers are exploring possibly delaying OA progression by intervening in ferroptosis