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conducted a randomized, double-blind, placebo-controlled (RDBPC) trial in 146 polysensitized AR pediatric patients randomly stratified into two groups, treated for 4 weeks with compound plus standard treatment or placebo plus standard treatment [63]

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Post-mortem studies of the autistic brain samples showed abnormal changes in the steady-state levels of complexes I-IV in the cingulate gyrus, cerebellum, thalamus, and temporal and frontal cortex [79, 80, 86, 122]