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Long-acting glucagon-like peptide-1 (GLP-1) analogues marketed for treatment of type 2 diabetes mellitus have been tested and have shown encouraging protective actions in experimental models of AD and PD as well as in initial clinical trials

In another 2006 clinical trial,(10)72 test subjects with pressure ulcers were presented with TB-500. The main aim of this randomized, double blind study was to establish the potential of thymosin beta 4 (analogous to TB-500) in ulcer presence

The TLR3 and TLR4 were the most abundant among TLR genes expressed in FLS, followed by members of the TLR2 subfamily

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